Design SuperiorNutraceuticals WithData-Driven Simulation
A design assistant that co-optimizes every target at once, finding the right molecular composition and processing parameters.
Co-optimize texture, stability, toxicity, bioavailability, manufacturability and activity, then own the market winners.
Trial and error, balancing many conflicting constraints
Raise the dose, the taste goes off. Thicken it, it stops dissolving. Boost absorption, shelf life drops. Cut the sugar, the texture collapses. Then whatever works still has to survive manufacturing, regulation and supply.
The project
A new R&D project is defined.
The targets
Target properties are defined, and they conflict. Fixing one ruins another.
The search
Hundreds of thousands of potential formulations. With expensive trial and error, only a few extremes can be tested.
The risk
Find that formulation and it still has to clear three more. Any one can end the program.
Backbond co-optimizes for all the targets simultaneously
The same four steps, answered. Backbond hands the lab a short list of formulations that already hit every target and already survive manufacturing, regulation and supply.
- Texture
- Define a Number
- Stability
- Define a Number
- Bioavailability
- Define a Number
- Toxicity
- Define a Number
- Activity
- Define a Number
Define
The product and the targets it must hit. Product: Liposomal magnesium complex for sleep and recovery
Simulate
Backbond builds thousands of digital twins and evaluates every one against the targets.
Rank
Ranked by the best balance across every target, and flagged by how confident Backbond is in each.
Test
The team proceeds to the lab with the most promising formulations. By default, these satisfy all targets and constraints.
How Backbond simulates a formulation candidate
Four levels of physics decide what a formulation actually does, and Backbond reasons about how all four interplay to set every spec.
A few example use cases
Every one is the same shape: a handful of targets that fight each other, and one formulation that has to hit them all.
Micellar casein precipitates in UHT. Find the casein grade, process parameters and excipient that ensure solubility, while holding encapsulation, shelf life and cost.
The capsule has to drop gelatin. Find an excipient that preserves bioavailability and is allergen free, without crumbling at scale-up or shifting gastric release.
Curcumin barely dissolves. Find the carrier, particle size and emulsifier that raise absorption, while holding heat stability, colour and cost.
Removing sugar collapses the gummy. Find the sweetener, humectant and gelling system that hold chew and shelf life, without polyol laxation or potency loss.
The fish oil emulsion oxidises and turns fishy. Find the antioxidant system and emulsifier that suppress oxidation, while holding bioavailability and mouthfeel.
Live cultures die in processing and on the shelf. Find the matrix, water activity and coating that hold CFU to 24 months, while keeping compressibility and gastric survival.
Iron and copper degrade vitamin C in the same tablet. Find the coating and blend order that preserve every active to end of shelf life, while holding hardness and disintegration.
TiO2 is out in the EU. Find the opacifier and coating that keep appearance and light protection, while holding the dissolution profile, printability and cost.
Magnesium and B-vitamins taste bitter and metallic. Find the masking system and coating that hide it, while holding disintegration time, clean label and cost.
A 600 mg dose makes a pill nobody will swallow. Find the excipient load and compression that shrink it, while holding hardness, disintegration and content uniformity.
The future
How Optagon Labs imagines the supplement company of the future, drawn work with hundreds of them: one brain coordinating specialised agents that work in parallel, running development end to end across the portfolio.
Coordinating work across every function